AUTHOR=Zhang Yang , Li Zongjuan , Chen Yixing , Tan Lijie , Zeng Zhaochong , Ding Jianyong , Du Shisuo TITLE=Induction Strategy for Locally Advanced Thymoma JOURNAL=Frontiers in Oncology VOLUME=Volume 11 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.704220 DOI=10.3389/fonc.2021.704220 ISSN=2234-943X ABSTRACT=Surgery is the mainstream treatment for thymoma. Complete surgical resection (R0) plays critical role in patient prognosis. However, for locally advanced thymoma (Masaoka-Koga stages III-IVa), achieving R0 resection remains challenging. Thus, attempts to achieve successful R0 resection, are urgently required. Obviously, inductive therapy is a promising strategy towards this aim. Herein, we review the recent progress achieved in preoperative treatment in locally advance thymoma, and discuss current difficulties and future directions.