AUTHOR=Zhang Yang , Li Zongjuan , Chen Yixing , Tan Lijie , Zeng Zhaochong , Ding Jianyong , Du Shisuo 

TITLE=Induction Strategy for Locally Advanced Thymoma

JOURNAL=Frontiers in Oncology

VOLUME=11

YEAR=2021

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.704220

DOI=10.3389/fonc.2021.704220

ISSN=2234-943X

ABSTRACT=<p>Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invasion of the disease. Induction treatment, with the aim of reducing bulky tumor mass, offers new strategy to facilitate totally surgical resection. Herein, we reviewed recent progress and provided a comprehensive overview of induction strategy in locally advance thymoma.</p>