AUTHOR=Crosetti Erika , Arrigoni Giulia , Sprio Andrea Elio , Succo Giovanni 

TITLE=“Fistula Zero” Project After Total Laryngectomy: The Candiolo Cancer Institute Experience

JOURNAL=Frontiers in Oncology

VOLUME=11

YEAR=2021

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.690703

DOI=10.3389/fonc.2021.690703

ISSN=2234-943X

ABSTRACT=<sec><title>Objectives</title><p>Pharyngocutaneous fistula (PCF) is a troublesome complication after total laryngectomy. The “Fistula zero” project aims to reduce the number of PCF by following a detailed protocol based on three fundamental key points.</p></sec><sec><title>Materials and Methods</title><p>The Fistula zero project included 77 patients who underwent total laryngectomy in the period from January 2019 to December 2020. The protocol consisted of three main aspects: the systematic placement of a Har-El salivary bypass tube, the continuous horizontal watertight pharyngeal suture using a barbed suture, onlay insetting of a pedicled flap in pre-treated patients.</p></sec><sec><title>Results</title><p>One case of PCF (1.3%) and three small blind fistulas (3.9%) were observed in this series. The mean length of hospitalization was 18 days.</p></sec><sec><title>Conclusion</title><p>Pharyngocutaneous fistula (PCF) prolongs hospitalization and delays adjuvant treatments. Thanks to a strict adherence to the protocol, it was possible to reduce PCF rates, avoiding lengthy hospitalization and additional surgical procedures.</p></sec>