AUTHOR=Kamposioras Konstantinos , Mauri Davide , Papadimitriou Konstantinos , Anthoney Alan , Hindi Nadia , Petricevic Branka , Dambrosio Mario , Valachis Antonis , Kountourakis Pantelis , Kopecky Jindrich , Kuhar Cvetka Grašič , Popovic Lazar , Chilingirova Nataliya P. , Zarkavelis George , de Mello Ramon Andrade , Plavetić Natalija Dedić , Christopoulos Christos , Mostert Bianca , Goffin John R. , Tzachanis Dimitiros , Saraireh Haytham Hamed , Ma Fei , Pavese Ida , Tolia Maria TITLE=Synthesis of Recommendations From 25 Countries and 31 Oncology Societies: How to Navigate Through Covid-19 Labyrinth JOURNAL=Frontiers in Oncology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.575148 DOI=10.3389/fonc.2020.575148 ISSN=2234-943X ABSTRACT=Introduction

Pandemic COVID-19 is an unexpected challenge for the oncological community, indicating potential detrimental effects on cancer patients. Our aim was to summarize the converging key points providing a general guidance in order to support decision making, pertaining to the oncologic care in the middle of a global outbreak.

Methods

We did an international online search in twenty five countries that have managed a surge in cancer patient numbers. We collected the recommendations from thirty one medical oncology societies.

Results

By synthesizing guidelines for a) oncology service delivery adjustments, b) general and specific treatment adaptations, and c) discrepancies from guidelines comparison, we present a clinical synopsis with the forty more crucial statements. A Covid-19 risk stratification base was also created in order to obtain a quick, objective patient assessment and a risk-benefit evaluation on a case-by-case basis.

Conclusions

In an attempt to face these complex needs and due to limited understanding of COVID-19, a variability of recommendations based on general epidemiological and infectious disease principles rather than definite cancer-related evidence has evolved. Additionally, the absence of an effective treatment or vaccine requires the development of cancer management guidance, capitalizing on comprehensive COVID-19 oncology experience globally.