AUTHOR=Sayan Mutlay , Serbez Ilkay , Teymur Bilgehan , Gur Gokhan , Zoto Mustafayev Teuta , Gungor Gorkem , Atalar Banu , Ozyar Enis TITLE=Patient-Reported Tolerance of Magnetic Resonance-Guided Radiation Therapy JOURNAL=Frontiers in Oncology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.01782 DOI=10.3389/fonc.2020.01782 ISSN=2234-943X ABSTRACT=Purpose

Magnetic resonance-guided radiation therapy (MRgRT) has been incorporated into a growing number of clinical practices world-wide, however, there is limited data on patient experiences with MRgRT. The purpose of this study was to prospectively evaluate patient tolerance of MRgRT using patient reported outcome questionnaires (PRO-Q).

Methods

Ninety patients were enrolled in this prospective observational study and treated with MRgRT (MRIdian Linac System, ViewRay Inc. Oakwood Village, OH, United States) between September 2018 and September 2019. Breath-hold-gated dose delivery with audiovisual feedback was completed as needed. Patients completed an in-house developed PRO-Q after the first and last fraction of MRgRT.

Results

The most commonly treated anatomic sites were the abdomen (47%) and pelvis (33%). Respiratory gating was utilized in 62% of the patients. Patients rated their experience as positive or at least tolerable with mean scores of 1.0–2.8. The most common complaint was the temperature in the room (61%) followed by paresthesias (57%). The degree of anxiety reported by 45% of the patients significantly decreased at the completion of treatment (mean score 1.54 vs. 1.36, p = 0.01). Forty-three percent of the patients reported some degree of disturbing noise which was improved considerably by use of music. All patients appreciated their active role during the treatment.

Conclusion

This evaluation of PROs indicates that MRgRT was well-tolerated by our patients. Patients’ experience may further improve with adjustment of room temperature and noise reduction.