AUTHOR=Escudero-Vilaplana Vicente , Calles Antonio , Collado-Borrell Roberto , Belén Marzal-Alfaro María , Polanco Carlos , Garrido Carmen , Suarez Jorge , Ortiz Aurora , Appierto Marilena , Comellas Marta , Lizán Luis 

TITLE=Standardizing Health Outcomes for Lung Cancer. Adaptation of the International Consortium for Health Outcomes Measurement Set to the Spanish Setting

JOURNAL=Frontiers in Oncology

VOLUME=10

YEAR=2020

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.01645

DOI=10.3389/fonc.2020.01645

ISSN=2234-943X

ABSTRACT=<p><bold>Purpose:</bold> Lung cancer (LC) and its treatment impose a significant burden on patients' life. However, patient-centered outcomes are rarely collected during patient follow-up. Filling this gap, the International Consortium for Health Outcomes Measurement (ICHOM) developed a standard set of variables for newly diagnosed LC patients. In order to facilitate the use of this standard set, the project aims to adapt it to the Spanish setting.</p><p><bold>Methods:</bold> The variables (instrument and periodicity) to be included in Spanish standard set were selected through consensus during 4 nominal groups (13 oncologists, 14 hospital pharmacists, 4 hospital managers and 3 LC patients), under the supervision of a Scientific Committee (1 oncologist, 3 hospital pharmacists, 2 LC patients advocates).</p><p><bold>Results:</bold> The variables agreed upon included: (1) case-mix: demographic [age, sex, education and social-family support], clinical [weight loss, smoking status, comorbidities (Charlson index), pulmonary function (FEV-1)], tumor [histology, clinical, and pathological stage (TNM), EGFR, ALK, ROS-1, PD-L1] and treatment factors [intent and completion] and (2) outcomes: degree of health [performance status (ECOG) and quality-of-life (EQ-5D, LCSS)], survival [overall survival and cause of death], quality of death [place of death, end-of-life care and palliative care, death aligned with living will], treatment complications, and others [date of diagnosis and treatment initiation, productivity loss (sick leave)].</p><p><bold>Conclusion:</bold> The adaptation of ICHOM standard set to the Spanish setting pave the way to standardize the collection of variables in LC.</p>