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Shiming Tan1†Pin Yi1,2†
Heran Wang1,3Longzheng Xia1Yaqian Han1Hui Wang1Biao Zeng1Lu Tang1,2Qing Pan1,2Yutong Tian1,2Shan Rao1Linda Oyang1Jiaxin Liang1Jinguan Lin1Min Su1Yingrui Shi1
Qianjin Liao1*Yujuan Zhou1*- 1Hunan Key Laboratory of Translational Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China
- 2Hunan Cancer Hospital, University of South China, Hengyang, China
- 3Hepatology Unit, Department of Infectious Disease, Nanfang Hospital, Southern Medical University, Guangzhou, China
A Corrigendum on
RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer
by Tan, S., Yi, P., Wang, H., Xia, L., Han, Y., Wang, H., et al. (2020). Front. Oncol. 10:649. doi: 10.3389/fonc.2020.00649
The authors regret that there was an error in Figure 6 due to incorrect image editing in Figure 6C. The correct Figure 6 appears below.
FIGURE 6
FIGURE 6. The effects of RAC1 expression in radiotherapy in vivo. (A) Representative photo of residual tumor of after 3*5 Gy dose of irradiation. (B) The time course of growth of Vector, RAC1, sh-control and sh-RAC1 xenograft tumors with or without IR treatment. (C) IHC staining showed an elevated Ki67 expression and upregulation of RAC1 in RAC1 overexpression xenograft tumor, which represents the radioresistant process in RAC1 overexpressing cells in vivo. Right panel showed a decreased Ki67 expression and downregulation of RAC1 in silencing RAC1 xenograft tumor, which represents the radiosensitivity process in sh-RAC1 cells in vivo. Down panel showed the quantification of scoring of immunostaining in RAC1 overexpression/silencing xenograft. Scale bar 100 μm. Data are expressed as the mean ± SD of different groups of cells from three separate experiments. *P < 0.05, **P < 0.01, ***P < 0.001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: RAC1, lung cancer, radioresistance, epithelial-to-mesenchymal transition, metastasis
Citation: Tan S, Yi P, Wang H, Xia L, Han Y, Wang H, Zeng B, Tang L, Pan Q, Tian Y, Rao S, Oyang L, Liang J, Lin J, Su M, Shi Y, Liao Q and Zhou Y (2020) Corrigendum: RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer. Front. Oncol. 10:1106. doi: 10.3389/fonc.2020.01106
Received: 26 May 2020; Accepted: 02 June 2020;
Published: 14 July 2020.
Edited and reviewed by: Boris Zhivotovsky, Karolinska Institutet (KI), Sweden
Copyright © 2020 Tan, Yi, Wang, Xia, Han, Wang, Zeng, Tang, Pan, Tian, Rao, Oyang, Liang, Lin, Su, Shi, Liao and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Qianjin Liao, bWFyY2gtb25AMTI2LmNvbQ==; Yujuan Zhou, eXVqYW55X3pob3VAMTYzLmNvbQ==
†These authors have contributed equally to this work