AUTHOR=Chen Wensheng , Chen Zhipeng , Zhang Miaomiao , Tian Yahui , Liu Lu , Lan Ruirui , Zeng Guandi , Fu Xiaolong , Ru Guoqing , Liu Wanting , Chen Liang , Fan Zhenzhen TITLE=GATA6 Exerts Potent Lung Cancer Suppressive Function by Inducing Cell Senescence JOURNAL=Frontiers in Oncology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.00824 DOI=10.3389/fonc.2020.00824 ISSN=2234-943X ABSTRACT=
Lung cancer is the leading cause of cancer-related deaths worldwide. Tumor suppressor genes (TSGs) play a critical role in restricting tumorigenesis and impact the therapeutic effect of various treatments. However, TSGs remain to be systemically determined in lung cancer. Here, we identified GATA6 as a potent lung cancer TSG. GATA6 inhibited lung cancer cell growth