AUTHOR=Rastrelli Marco , Del Fiore Paolo , Buja Alessandra , Vecchiato Antonella , Rossi Carlo Riccardo , Chiarion Sileni Vanna , Tropea Saveria , Russano Francesco , Zorzi Manuel , Spina Romina , Cappellesso Rocco , Mazzarotto Renzo , Cavallin Francesco , Bassetto Franco , Bezzon Elisabetta , Ferrazzi Beatrice , Alaibac Mauro , Mocellin Simone TITLE=A Therapeutic and Diagnostic Multidisciplinary Pathway for Merkel Cell Carcinoma Patients JOURNAL=Frontiers in Oncology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.00529 DOI=10.3389/fonc.2020.00529 ISSN=2234-943X ABSTRACT=

Merkel Cell Carcinoma (MCC) is a highly aggressive neuroendocrine neoplasm of the skin. Due to its rarity, the management of MCC is not standardized across centers. In this article, we present the experience of the Veneto region in the North-East of Italy, where a committee of skin cancer experts has proposed a clinical pathway for the diagnosis and treatment of MCC. Putting together the evidence available in the international literature, we outlined the best approach to the management of patients affected with this malignancy step- by- step for each possible clinical situation. Crucial in this pathway is the role of the multidisciplinary team to deal with the lack of robust information on each aspect of the management of this disease.