AUTHOR=Kubasch Anne Sophie , Franke Georg-Nikolaus , Aldaoud Ali , Weibl Konstantin , Jentzsch Madlen , Sabri Osama , Horny Hans-Peter , Fend Falko , Behre Gerhard , Platzbecker Uwe , Vucinic Vladan 

TITLE=Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma

JOURNAL=Frontiers in Oncology

VOLUME=10

YEAR=2020

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.00219

DOI=10.3389/fonc.2020.00219

ISSN=2234-943X

ABSTRACT=<p>Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here presented first report about successful allogeneic hematopoietic stem cell transplantation leading to remission in a case of tonsillar MCS represents a promising potential curative treatment option for this rare and often fatal disease.</p>