AUTHOR=Birch Gavin P. , Campbell Thane , Bradley Mark , Dhaliwal Kevin TITLE=Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine–An Emerging Strategy JOURNAL=Frontiers in Oncology VOLUME=9 YEAR=2019 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2019.00882 DOI=10.3389/fonc.2019.00882 ISSN=2234-943X ABSTRACT=

The optical molecular imaging of inflammation is an emerging strategy for interventional medicine and diagnostics. The host's inflammatory response and adaptation to acute and chronic diseases provides unique signatures that have the potential to guide interventions. Thus, there are emerging a suite of molecular imaging and sensing approaches for a variety of targets in this area. This review will focus on two key cellular orchestrators that dominate this area, neutrophils and macrophages, with recent developments in molecular probes and approaches discussed.