AUTHOR=Jethanandani Amit , Gule-Monroe Maria K. , Chen Melissa , Johnson Jason M. 

TITLE=Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation

JOURNAL=Frontiers in Oncology

VOLUME=9

YEAR=2019

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2019.00373

DOI=10.3389/fonc.2019.00373

ISSN=2234-943X

ABSTRACT=<p>Distant metastatic disease from gliomas is extremely rare. We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. The presence of an H3F3A mutation in these patients may indicate further work-up to include intensive staging examination.</p>