AUTHOR=Alfarouk Khalid O. , Bashir Adil H. H. , Aljarbou Ahmed N. , Ramadan AbdelRahman M. , Muddathir Abdel Khalig , AlHoufie Sari T. S. , Hifny Abdelhamid , Elhassan Gamal O. , Ibrahim Muntaser E. , Alqahtani Saad S. , AlSharari Shakir D. , Supuran Claudiu T. , Rauch Cyril , Cardone Rosa Angela , Reshkin Stephan J. , Fais Stefano , Harguindey Salvador 

TITLE=The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

JOURNAL=Frontiers in Oncology

VOLUME=9

YEAR=2019

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2019.00075

DOI=10.3389/fonc.2019.00075

ISSN=2234-943X

ABSTRACT=<p><italic>Helicobacter pylori</italic> (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of HP inducing gastric cancer offers the potential strategy in the managing of HP rather than eradicating it. In this article, we try to summarize the biology of HP-induced gastric cancer and discuss the current pharmacological approach to treat and prevent its carcinogenicity.</p>