AUTHOR=González Maraelys Morales , Aguilar Claudia Hernández , Pacheco Flavio Arturo Domínguez , Cabrales Luis Enrique Bergues , Reyes Juan Bory , Nava Juan José Godina , Ambrosio Paulo Eduardo , Domiguez Dany Sanchez , Sierra González Victoriano Gustavo , Pupo Ana Elisa Bergues , Ciria Héctor Manuel Camué , Alemán Elizabeth Issac , García Francisco Monier , Rivas Clara Berenguer , Reina Evelyn Chacón 

TITLE=Tissue Damage, Temperature, and pH Induced by Different Electrode Arrays on Potato Pieces (Solanum tuberosum L.)

JOURNAL=Frontiers in Oncology

VOLUME=8

YEAR=2018

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2018.00101

DOI=10.3389/fonc.2018.00101

ISSN=2234-943X

ABSTRACT=<p>One of the most challenging problems of electrochemical therapy is the design and selection of suitable electrode array for cancer. The aim is to determine how two-dimensional spatial patterns of tissue damage, temperature, and pH induced in pieces of potato (<italic>Solanum tuberosum</italic> L., var. Mondial) depend on electrode array with circular, elliptical, parabolic, and hyperbolic shape. The results show the similarity between the shapes of spatial patterns of tissue damage and electric field intensity, which, like temperature and pH take the same shape of electrode array. The adequate selection of suitable electrodes array requires an integrated analysis that involves, in a unified way, relevant information about the electrochemical process, which is essential to perform more efficiently way the therapeutic planning and the personalized therapy for patients with a cancerous tumor.</p>