AUTHOR=SAMPOR CLAUDIA V., Guthmann Marcelo D., Scursoni Alejandra , Cacciavillano Walter , Torbidoni Ana , Galluzzo Laura , Camarero Sandra , Lopez Jessica , Garcia de Davila Maria Teresa , Fainboim Leonardo , Chantada Guillermo 

TITLE=Immune response to racotumomab in a child with relapsed neuroblastoma

JOURNAL=Frontiers in Oncology

VOLUME=2

YEAR=2012

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2012.00195

DOI=10.3389/fonc.2012.00195

ISSN=2234-943X

ABSTRACT=<p>Immunotherapy targeting ganglioside antigens is a powerful tool for the treatment of high risk neuroblastoma. However, only treatment with anti-GD2 antibodies has been used in clinical practice and other options may be pursued. We report the use of racotumomab, an anti-idiotype vaccine against N-glycolyl neuraminic acid (NeuGc)- containing gangliosides, eliciting an immune response in a child with relapsed neuroblastoma expressing the NeuGcGM3 ganglioside.</p>