AUTHOR=Zhao Shiao , Zhang Hong , Xu Yipin , Li Jiarui , Du Senyao , Ning Ziheng TITLE=The effect of protein intake on athletic performance: a systematic review and meta-analysis JOURNAL=Frontiers in Nutrition VOLUME=11 YEAR=2024 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1455728 DOI=10.3389/fnut.2024.1455728 ISSN=2296-861X ABSTRACT=Background

The impact of a protein-rich diet and protein supplements on athletic performance remains a topic of debate. Does protein intake offer benefits for athletes? If so, which specific aspects of athletic performance are most influenced by protein?

Methods

This study aimed to explore the relationship between protein intake and athletic performance. A systematic database search was conducted to identify randomized controlled trials (RCTs) examining the effects of protein intake on athletes’ performance. The databases searched included PubMed, Scopus, Web of Science, EBSCO, and Ovid. The meta-analysis included a total of 28 studies involving 373 athletes. The meta-analysis employed both the fixed-effects model and the random-effects model to investigate the impact of protein intake on sports performance. Subgroup analyses were conducted to provide solid evidence to explain the results of the meta-analysis. Sensitive analysis and funnel plots were used to assess the risk of bias and data robustness.

Results

Overall, protein intake did not show a statistically significant improvement in athletic performance (standardized mean difference [SMD] = 0.12, 95% confidence interval [CI]: −0.01 to 0.25). However, in subgroup analysis, the protein group demonstrated a statistically significant improvement in endurance performance, as indicated by the forest plot of final values (SMD = 0.17, 95% CI: 0.02 to 0.32). Additionally, the change value in the forest plot for endurance performance showed even greater statistical significance than the final value (SMD = 0.31, 95% CI: 0.15 to 0.46). In the subgroup analysis based on physiological indices, muscle glycogen showed a statistically significant improvement in the protein group (standardized mean difference [SMD] = 0.74, 95% confidence interval [CI]: 0.02 to 0.32). Furthermore, subgroup analyses based on protein supplementation strategies revealed that co-ingestion of protein and carbohydrates (CHO) demonstrated statistically significant improvements in endurance performance (SMD = 0.36, 95% CI: 0.11 to 0.61), whereas high protein intake alone did not.

Conclusion

Protein intake appears to provide modest benefits to athletes in improving their performance, particularly by enhancing endurance. Subgroup analysis suggests that protein intake improves muscle glycogen levels and that the co-ingestion of protein with CHO is more effective for endurance athletes than high protein intake alone.

Systematic review registration

https://www.crd.york.ac.uk/prospero/, Identifier CRD42024508021.