AUTHOR=Zhu Ling , Guan Lijun , Wang Kunlun , Ren Chuanying , Gao Yang , Li Jialei , Yan Song , Zhang Xindi , Yao Xinmiao , Zhou Ye , Li Bo , Lu Shuwen 

TITLE=Recent trends in extraction, purification, structural characterization, and biological activities evaluation of Perilla frutescens (L.) Britton polysaccharide

JOURNAL=Frontiers in Nutrition

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1359813

DOI=10.3389/fnut.2024.1359813

ISSN=2296-861X

ABSTRACT=<p><italic>Perilla frutescens</italic> (L.) Britton is an annual herb plant of the <italic>Perilla</italic> genus in the Labiatae family, which is commonly utilized as an edible and medicinal resource. Polysaccharides are among the major components and essential bioactive compounds of <italic>P. frutescens</italic>, which exhibit a multitude of biological activities, including antioxidant, antitumor, anti-fatigue, immunoregulation, hepatoprotective, anti-inflammatory, and lipid-lowering effects. As a natural carbohydrate, <italic>P. frutescens</italic> polysaccharide has the potential to be utilized in the development of drugs and functional materials. In this paper, we provide an overview of progress made on the extraction, purification, structural characterization, and bioactivity of polysaccharides from different parts of <italic>P. frutescens</italic>. The challenges and opportunities for research are discussed, along with the potential development prospects and future areas of focus in the study of <italic>P. frutescens</italic> polysaccharides.</p>