AUTHOR=Zaccone Vincenzo , Santoro Luca , Guerrieri Emanuele , Diblasi Ilaria , Roncarati Ilaria , Viticchi Giovanna , Vecchiarelli Pietro , Santoliquido Angelo , Fiore Francesca , Molfino Alessio , Landi Francesco , Moroncini Gianluca , Gasbarrini Antonio , Muscaritoli Maurizio , Falsetti Lorenzo 

TITLE=Prevention and treatment of catheter-related venous thrombosis in long-term parenteral nutrition: A SINuC position statement

JOURNAL=Frontiers in Nutrition

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1106327

DOI=10.3389/fnut.2023.1106327

ISSN=2296-861X

ABSTRACT=<p>The implementation of long-term parenteral nutrition (PN) often requires the placement of central venous access, a procedure that carries a considerable risk of catheter-related venous thrombosis (CRT). The occurrence of CRT represents a major event in the natural history of patients in PN since it can lead to central venous access loss and PN failure. Despite the importance of this topic in clinical nutrition, the prevention and treatment of CRT in PN represents one of the “gray areas” of the literature of the presence of few randomized controlled clinical trials and the generally low level of evidence of published scientific papers. Through a narrative review of the literature and a Delphi consensus, the Italian Society of Clinical Nutrition and Metabolism (SINuC) aimed to collect some practical recommendations regarding the current state-of-the-art in the prevention, diagnosis, and treatment of CRT in patients undergoing long-term PN.</p>