AUTHOR=Musazadeh Vali , Zarezadeh Meysam , Ghalichi Faezeh , Kalajahi Fateme Hamedi , Ghoreishi Zohreh 

TITLE=Vitamin D supplementation positively affects anthropometric indices: Evidence obtained from an umbrella meta-analysis

JOURNAL=Frontiers in Nutrition

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.980749

DOI=10.3389/fnut.2022.980749

ISSN=2296-861X

ABSTRACT=<p>Despite the growing evidence from meta-analyses on vitamin D’s anti-obesity properties, their results are controversial. The current umbrella review was performed to assess the available evidence and provide a conclusive explanation in this regard. The international databases PubMed, Scopus, Embase, Web of Science and Google Scholar were systematically searched till March, 2022. A random-effects model was used to run the meta-analysis. All meta-analyses that examined the effect of vitamin D supplementation on BW, BMI, WC, and fat mass were included. Findings of 14 meta-analyses revealed that vitamin D supplementation reduced body mass index (BMI) (ES: −0.11 kg/m<sup>2</sup>; 95% CI: −0.18, −0.05, <italic>p</italic>?0.001; <italic>I</italic><sup>2</sup> = 61.0%, <italic>p</italic> &lt; 0.001), and waist circumference (WC) (ES = −0.79 cm; 95% CI: −1.20, −0.37; <italic>p</italic> &lt; 0.001; <italic>I</italic><sup>2</sup> = 46.5%, <italic>p</italic> = 0.096) in comparison to control group. However, the effects of vitamin D on body weight (ES = −0.16 kg, 95% CI: −0.36, 0.04; <italic>p</italic> = 0.125; <italic>I</italic><sup>2</sup> = 57.0%, <italic>p</italic> = 0.017), and fat mass (ES: 0.02, 95% CI: −0.20, 0.24, <italic>p</italic> = 0.868; <italic>I</italic><sup>2</sup> = 0.0%, <italic>p</italic> = 0.531) were not considerable. Vitamin D supplementation significantly improved levels of obesity indices such as BMI, and WC.</p>