AUTHOR=He Yuan , Li Lin , Chang Hao , Cai Bin , Gao Huajun , Chen Guoyu , Hou Wen , Jappar Zubaydan , Yan Yizhe 

TITLE=Research progress on extraction, purification, structure and biological activity of Dendrobium officinale polysaccharides

JOURNAL=Frontiers in Nutrition

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.965073

DOI=10.3389/fnut.2022.965073

ISSN=2296-861X

ABSTRACT=<p><italic>Dendrobium officinale</italic> Kimura et Migo (<italic>D. officinale</italic>) is a traditional medicinal and food homologous plant that has been used for thousands of years in folk medicine and nutritious food. Recent studies have shown that polysaccharide is one of the main biologically active components in <italic>D. officinale</italic>. <italic>D. officinale</italic> polysaccharides possess several biological activities, such as anti-oxidant, heptatoprotective, immunomodulatory, gastrointestinal protection, hypoglycemic, and anti-tumor activities. In the past decade, polysaccharides have been isolated from <italic>D. officinale</italic> by physical and enzymatic methods and have been subjected to structural characterization and activity studies. Progress in extraction, purification, structural characterization, bioactivity, structure-activity relationship, and possible bioactivity mechanism of polysaccharides <italic>D. officinale</italic> were reviewed. In order to provide reference for the in-depth study of <italic>D. officinale</italic> polysaccharides and the application in functional food and biomedical research.</p>