AUTHOR=Reis Fabricio Moreira , da Silva Maryanne Zilli Canedo , Reis Nayrana Soares do Carmo , Costa Fabiana Lourenço , da Silveira Caroline Ferreira da Silva Mazeto Pupo , Barretti Pasqual , Martin Luis Cuadrado , Bazan Silméia Garcia Zanati TITLE=Association between phase angle and coronary artery calcium score in patients on peritoneal dialysis JOURNAL=Frontiers in Nutrition VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.912642 DOI=10.3389/fnut.2022.912642 ISSN=2296-861X ABSTRACT=Introduction

The phase angle (PhA) has been used as a nutritional marker and predictor of mortality in patients on peritoneal dialysis (PD). The coronary artery calcium (CAC) score has shown to predict the incidence of acute myocardial infarction and death from cardiovascular disease in these patients. However, the association between PhA and CAC score in patients with PD is not well-established, which is the objective of this study.

Materials and methods

Cross-sectional study with patients on PD, followed up at a University Hospital, between March 2018 and August 2019. PhA was evaluated by unifrequency bioimpedance (BIA). The CAC score was calculated based on cardiovascular computed tomography, considering positive when greater than or equal to 100 Agatston and negative when less than 100 Agatston.

Results

We evaluated 44 patients on dialysis, with a mean age of 56 years and median time on dialysis therapy was 11.7 months. In the statistical analysis, a significant association was only observed between the CAC score and the PhA.

Conclusion

The PhA is associated with a positive CAC score in patients with PD, and despite other factors, may be useful as a risk marker for coronary artery disease in this population.