AUTHOR=Li Ying , Gao Junshan , Xue Liang , Shang Yanyan , Cai Weicheng , Xie Xinqiang , Jiang Tong , Chen Huizhen , Zhang Jumei , Wang Juan , Chen Moutong , Ding Yu , Wu Qingping TITLE=Determination of Antiviral Mechanism of Centenarian Gut-Derived Limosilactobacillus fermentum Against Norovirus JOURNAL=Frontiers in Nutrition VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.812623 DOI=10.3389/fnut.2022.812623 ISSN=2296-861X ABSTRACT=
Although noroviruses are the causative agents of most non-bacterial foodborne disease outbreaks, effective antivirals are currently unavailable. Certain probiotic strains have been reported as active antivirals for norovirus infections, but their mechanisms have not been fully elucidated. Herein, we examined the antiviral potential of 122 lactic acid bacteria isolates against murine norovirus (MNV), a human norovirus surrogate. A centenarian gut-derived strain,