AUTHOR=Tang Jiaming , Zheng Xiaoling , Jiang Shuang , Cao Mingdong , Wang Sixian , Zhou Zhaoyang , Nie Xunqing , Fang Yu , Le Tao TITLE=Dual fluorescent aptasensor for simultanous and quantitative detection of sulfadimethoxine and oxytetracycin residues in animal-derived foods tissues based on mesoporous silica JOURNAL=Frontiers in Nutrition VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.1077893 DOI=10.3389/fnut.2022.1077893 ISSN=2296-861X ABSTRACT=
Herein, we developed a dual fluorescent aptasensor based on mesoporous silica to simultaneously detect sulfadimethoxine (SDM) and oxytetracycline (OTC) in animal-derived foods. We immobilized two types of aptamers modified with FAM and CY5 on the silica surface by base complementary pairing reaction with the cDNA modified with a carboxyl group and finally formed the aptasensor detection platform. Under optimal conditions, the detection range of the aptasensor for SDM and OTC was 3–150 ng/mL (