AUTHOR=Striegel Lisa , Chebib Soraya , Dumler Caroline , Lu Yuyun , Huang Dejian , Rychlik Michael TITLE=Durian Fruits Discovered as Superior Folate Sources JOURNAL=Frontiers in Nutrition VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2018.00114 DOI=10.3389/fnut.2018.00114 ISSN=2296-861X ABSTRACT=

Durian (Durio zibethinus) is a tropical fruit grown in Southeast Asia and highly appreciated by consumers throughout Asia. Folates are a group of vitamins and are essential nutrients for humans. Here we present the folate analysis of different durian cultivars as well as diverse durian products. An LC-MS/MS method and the application of a stable isotope dilution assay (SIDA) was used for quantitation of the folate vitamers 5-methyltetrahydrofolate, 5-formyltetrahydrofolate, 10-formylfolate, tetrahydrofolate, and pteroylmonoglutamic acid by using [13C5]-labeled internal standards. Total folates varied from 175 to 440 μg/100 g for durian arils and from 15.0 to 417 μg/100 g for durian products. These contents are extraordinarily high compared to other fruits and may be correlated to the upregulated methionine biosynthesis pathway reported recently. In summary, the tropical fruit durian can be considered as a very rich dietary source of natural folates.