AUTHOR=Wada Yasuaki , Komatsu Yosuke , Izumi Hirohisa , Shimizu Takashi , Takeda Yasuhiro , Kuwahata Masashi TITLE=Increased Ratio of Non-mercaptalbumin-1 Among Total Plasma Albumin Demonstrates Potential Protein Undernutrition in Adult Rats JOURNAL=Frontiers in Nutrition VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2018.00064 DOI=10.3389/fnut.2018.00064 ISSN=2296-861X ABSTRACT=
The redox state of plasma albumin shifts in response to dietary protein intake in growing rats, and the shift is more sensitive than that of plasma albumin level, a classical marker of protein nutritional status. While it has been suggested that plasma albumin redox state could be useful as a novel marker of protein nutritional status, the above animal model is highly sensitive to dietary protein intake and the observation may not be extrapolated widely to humans. This study aimed to investigate whether albumin redox state also reflects protein nutritional status in adult rats, which have a lower dietary protein requirement and are less responsive to protein intake. Male adult rats were placed on AIN-93M diet (14% casein), or AIN-93M-based low protein diets (10 or 5% casein)