AUTHOR=Schramm Georg , Thielemans Kris TITLE=PARALLELPROJ—an open-source framework for fast calculation of projections in tomography JOURNAL=Frontiers in Nuclear Medicine VOLUME=3 YEAR=2024 URL=https://www.frontiersin.org/journals/nuclear-medicine/articles/10.3389/fnume.2023.1324562 DOI=10.3389/fnume.2023.1324562 ISSN=2673-8880 ABSTRACT=

In this article, we introduce parallelproj, a novel open-source framework designed for efficient parallel computation of projections in tomography leveraging either multiple CPU cores or GPUs. This framework efficiently implements forward and back projection functions for both sinogram and listmode data, utilizing Joseph’s method, which is further extended to encompass time-of-flight (TOF) PET projections. Our evaluation involves a series of tests focusing on PET image reconstruction using data sourced from a state-of-the-art clinical PET/CT system. We thoroughly benchmark the performance of the projectors in non-TOF and TOF, sinogram, and listmode employing multi CPU-cores, hybrid CPU/GPU, and exclusive GPU mode. Moreover, we also investigate the timing of non-TOF sinogram projections calculated in STIR (Software for Tomographic Image Reconstruction) which recently integrated parallelproj as one of its projection backends. Our results indicate that the exclusive GPU mode provides acceleration factors between 25 and 68 relative to the multi-CPU-core mode. Furthermore, we demonstrate that OSEM listmode reconstruction of state-of-the-art real-world PET data sets is achievable within a few seconds using a single consumer GPU.