AUTHOR=Ruan Dan , Sun Long 

TITLE=Case Report: Pleuropulmonary Blastoma in a 2.5-Year-Old Boy: 18F-FDG PET/CT Findings

JOURNAL=Frontiers in Nuclear Medicine

VOLUME=1

YEAR=2021

URL=https://www.frontiersin.org/journals/nuclear-medicine/articles/10.3389/fnume.2021.780485

DOI=10.3389/fnume.2021.780485

ISSN=2673-8880

ABSTRACT=<p>Pleuropulmonary blastoma (PPB) is a rare invasive primary malignancy in the thoracic cavity that occurs mainly in infants and children. It is often misdiagnosed and not treated correctly and promptly due to the lack of specificity of clinical symptoms and conventional imaging presentations. We report a 2.5-year-old boy who underwent X-ray chest radiography, chest CT, and <sup>18</sup>F-FDG PET/CT. PET/CT images demonstrated a sizeable cystic-solid mass with heterogeneous increased glucose metabolism in the left thoracic cavity. The diagnosis of PPB (type II) was finally confirmed by a CT-guided puncture biopsy of the active tumor tissue. This case highlights the critical role of <sup>18</sup>F-FDG PET/CT in the diagnosis of PPB in children.</p>