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CASE REPORT article
Front. Neurosci.
Sec. Autonomic Neuroscience
Volume 19 - 2025 | doi: 10.3389/fnins.2025.1529183
Case report: Sympathetic nerve block treat chronic kidney diseaseassociated pruritus
Provisionally accepted- 1 Department of Anesthesiology, 山西白求恩医院，山西医科大学第三临床医学院, 太原市, China
- 2 Department of Anesthesiology, Shanxi Medical University, Taiyuan, 030001, China, Taiyuan, Shanxi Province, China
- 3 Department of Nephrology, 山西白求恩医院，山西医科大学第三临床医学院, 太原市, China
Uremia is the advanced stage of chronic kidney disease (CKD), characterized by the accumulation of metabolic waste products in the blood as a result of the kidneys' inability to meet the body's metabolic demands (1) . Patients with uremia frequently experience a range of complications, including renal anemia, osteoporosis, and cardiovascular disease, all of which significantly impair their quality of life. Chronic kidney disease-associated pruritus (CKD-aP) is a common comorbidity in uremic patients, particularly among those undergoing hemodialysis, with prevalence rates ranging from 10% to 77% .This case report enrolled three patients diagnosed with chronic kidney disease-associated pruritus (CKD-ap) who underwent ultrasound-guided sympathetic nerve blockade procedures. The results demonstrated significant reductions in pruritus intensity concurrent with measurable enhancements in sleep quality and daily functioning.
Keywords: CKD-aP 1, uremia 2, sympathetic nerve block 3, chronic kidney disease 4, Autonomic Nervous System 5
Received: 16 Nov 2024; Accepted: 31 Mar 2025.
Copyright: © 2025 Li, Chen, Nie, Huang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Weiwei Zhang, Department of Anesthesiology, 山西白求恩医院，山西医科大学第三临床医学院, 太原市, China
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