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REVIEW article
Front. Neurosci.
Sec. Sleep and Circadian Rhythms
Volume 19 - 2025 |
doi: 10.3389/fnins.2025.1428733
Role of Sleep in Alzheimer's Disease: A mini review
Provisionally accepted- Beacon Biosignals, Boston, United States
Sleep is a stereotyped and well-preserved series of neurophysiological states that are essential for overall health and brain functioning. Emerging research suggests that sleep disturbances are not only associated with but also causally contribute to neurodegenerative disease onset and progression. This mini-review examines some of the current knowledge and evidence for relationships between sleep abnormalities and Alzheimer's disease within context of possible uses and limitations of sleep biomarkers for evaluation of Alzheimer's disease. Understanding these relationships could lead to readily accessible and easily quantifiable biomarkers of Alzheimer's dementia.
Keywords: Sleep, Alzheimer disease, review, Sleep monitoring, neurodegenerative disease
Received: 13 May 2024; Accepted: 13 Jan 2025.
Copyright: © 2025 Pathmanathan, Westover, Donoghue and Sivakumaran. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jay Pathmanathan, Beacon Biosignals, Boston, United States
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.