AUTHOR=Huang Ruisen , Hong Keum-Shik , Bao Shi-Chun , Gao Fei TITLE=Real-time motion artifact suppression using convolution neural networks with penalty in fNIRS JOURNAL=Frontiers in Neuroscience VOLUME=18 YEAR=2024 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1432138 DOI=10.3389/fnins.2024.1432138 ISSN=1662-453X ABSTRACT=Introduction

Removing motion artifacts (MAs) from functional near-infrared spectroscopy (fNIRS) signals is crucial in practical applications, but a standard procedure is not available yet. Artificial neural networks have found applications in diverse domains, such as voice and image processing, while their utility in signal processing remains limited.

Method

In this work, we introduce an innovative neural network-based approach for online fNIRS signals processing, tailored to individual subjects and requiring minimal prior experimental data. Specifically, this approach employs one-dimensional convolutional neural networks with a penalty network (1DCNNwP), incorporating a moving window and an input data augmentation procedure. In the training process, the neural network is fed with simulated data derived from the balloon model for simulation validation and semi-simulated data for experimental validation, respectively.

Results

Visual validation underscores 1DCNNwP’s capacity to effectively suppress MAs. Quantitative analysis reveals a remarkable improvement in signal-to-noise ratio by over 11.08 dB, surpassing the existing methods, including the spline-interpolation, wavelet-based, temporal derivative distribution repair with a 1 s moving window, and spline Savitzky-Goaly methods. Contrast-to-noise ratio (CNR) analysis further demonstrated 1DCNNwP’s ability to restore or enhance CNRs for motionless signals. In the experiments of eight subjects, our method significantly outperformed the other approaches (except offline TDDR, t < −3.82, p < 0.01). With an average signal processing time of 0.53 ms per sample, 1DCNNwP exhibited strong potential for real-time fNIRS data processing.

Discussion

This novel univariate approach for fNIRS signal processing presents a promising avenue that requires minimal prior experimental data and adapts seamlessly to varying experimental paradigms.