Skip to main content

MINI REVIEW article

Front. Neurosci.
Sec. Neuropharmacology
Volume 18 - 2024 | doi: 10.3389/fnins.2024.1425532
This article is part of the Research Topic New Players on the Monoaminergic Field: Relevance to the Mental Disorder View all 6 articles

Cannabinoids and monoaminergic system: implications for learning and memory

Provisionally accepted
莎 赵 莎 赵 Zhao Liang Gu Zhao Liang Gu YaNan Yue YaNan Yue Xia Zhang Xia Zhang Yuan Dong Yuan Dong *
  • Qingdao University, Qingdao, China

The final, formatted version of the article will be published soon.

    Cannabinoids and the endocannabinoid system (ECS) have been intensively studied for their neuroregulatory roles in the central nervous system (CNS), especially in regulating learning and memory. However, many experimental and clinical studies obtained conflicting results indicating a complex network of interaction underlying the regulation of learning and memory by different cannabinoids and the ECS. The ECS influences neuronal synaptic communications, and therefore may exert different regulation via their different impact on other neurotransmitters. The monoaminergic system includes a variety of neurotransmitters, such as dopamine, norepinephrine, and serotonin, which play important roles in regulating mood, cognition, and reward. The interaction among cannabinoids, ECS and the monoaminergic system has drawn particular attention, especially their contributions to learning and memory.In this review, we summarized the current understanding of how cannabinoids, ECS and the monoaminergic system contribute to the process of learning and memory, and discussed the influences of monoaminergic neurotransmission by cannabinoids and ECS during this process.

    Keywords: endocannabinoid, monoamines, Learning, Memory, Dopamine, Serotonin

    Received: 29 Apr 2024; Accepted: 26 Jul 2024.

    Copyright: © 2024 赵, Gu, Yue, Zhang and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yuan Dong, Qingdao University, Qingdao, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.