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REVIEW article

Front. Neurosci.
Sec. Neurodegeneration
Volume 18 - 2024 | doi: 10.3389/fnins.2024.1414603

Scoping review of epigenetics on neurodegenerative diseases: Research frontiers and publication status

Provisionally accepted
Yanyan Zhang Yanyan Zhang Qiangqiang Fu Qiangqiang Fu Xiaoguang Zhang Xiaoguang Zhang Dong Zhang Dong Zhang Yunhua Yue Yunhua Yue Chuanxi Yang Chuanxi Yang *
  • Yangpu Hospital, Tongji University School of Medicine, Shanghai, China

The final, formatted version of the article will be published soon.

    Aims: Epigenetics has significantly evolved and emerged as important players in the pathogenesis of neurodegenerative diseases. However, a scientometric synthesis of such changes over time is currently lacking.We conducted a comprehensive search of the Web of Science Core Collection from inception until November 5, 2022, using appropriate keywords. Our primary objective was to employ scientometric analysis to depict changes in keywords over time and to assess the structure and credibility of clusters. Additionally, we examined the network of research (countries, institutions, and authors) using CiteSpace and VOSviewer.We identified 25 clusters with well-structured networks (Q=0.82) and highly credible clustering (S=0.91) from 16,181 articles published between 1999 and 2022. Our findings are as follows:(a) the literature and research interest concerning the epigenetics of neurodegenerative diseases are continuously growing; (b) the three most productive countries are the USA, China, and Germany; (c) international collaborative relationships exist, alongside small, isolated collaboration networks of individual institutions.The number and impact of global publications on the epigenetics of neurodegenerative diseases have expanded rapidly over the past 20 years. This review provides valuable guidelines for researchers interested in neurodegenerative diseases research.

    Keywords: Scientometric, Neurodegenerative Diseases, epigenetics, Evidence synthesis, hotspots

    Received: 09 Apr 2024; Accepted: 30 Sep 2024.

    Copyright: © 2024 Zhang, Fu, Zhang, Zhang, Yue and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Chuanxi Yang, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.