AUTHOR=Wu Zelin , Zhang Xueying , Li Fenglian , Wang Suzhe , Li Jiaying TITLE=TransRender: a transformer-based boundary rendering segmentation network for stroke lesions JOURNAL=Frontiers in Neuroscience VOLUME=17 YEAR=2023 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1259677 DOI=10.3389/fnins.2023.1259677 ISSN=1662-453X ABSTRACT=

Vision transformer architectures attract widespread interest due to their robust representation capabilities of global features. Transformer-based methods as the encoder achieve superior performance compared to convolutional neural networks and other popular networks in many segmentation tasks for medical images. Due to the complex structure of the brain and the approximate grayscale of healthy tissue and lesions, lesion segmentation suffers from over-smooth boundaries or inaccurate segmentation. Existing methods, including the transformer, utilize stacked convolutional layers as the decoder to uniformly treat each pixel as a grid, which is convenient for feature computation. However, they often neglect the high-frequency features of the boundary and focus excessively on the region features. We propose an effective method for lesion boundary rendering called TransRender, which adaptively selects a series of important points to compute the boundary features in a point-based rendering way. The transformer-based method is selected to capture global information during the encoding stage. Several renders efficiently map the encoded features of different levels to the original spatial resolution by combining global and local features. Furthermore, the point-based function is employed to supervise the render module generating points, so that TransRender can continuously refine the uncertainty region. We conducted substantial experiments on different stroke lesion segmentation datasets to prove the efficiency of TransRender. Several evaluation metrics illustrate that our method can automatically segment the stroke lesion with relatively high accuracy and low calculation complexity.