AUTHOR=Zhao Qing , Du Xinxin , Chen Wenhong , Zhang Ting , Xu Zhuo 

TITLE=Advances in diagnosing mild cognitive impairment and Alzheimer’s disease using 11C-PIB- PET/CT and common neuropsychological tests

JOURNAL=Frontiers in Neuroscience

VOLUME=17

YEAR=2023

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1216215

DOI=10.3389/fnins.2023.1216215

ISSN=1662-453X

ABSTRACT=<p>Alzheimer’s disease (AD) is a critical health issue worldwide that has a negative impact on patients’ quality of life, as well as on caregivers, society, and the environment. Positron emission tomography (PET)/computed tomography (CT) and neuropsychological scales can be used to identify AD and mild cognitive impairment (MCI) early, provide a differential diagnosis, and offer early therapies to impede the course of the illness. However, there are few reports of large-scale <sup>11</sup>C-PIB-PET/CT investigations that focus on the pathology of AD and MCI. Therefore, further research is needed to determine how neuropsychological test scales and PET/CT measurements of disease progression interact.</p>