The purpose of this study was to study in retina thickness changes in myopic mice using optical coherence tomography (OCT).
There were 18 mice in the form-deprivation myopia (FDM) group,in which the left eye was not treated as a control;18 untreated mice served as a normal control group. The diopter of all mice was measured 21 days after birth (P21), before form deprivation. After 4 weeks of form deprivation (P49), the refraction, fundus, and retinal sublayer thickness of all mice were measured.
After 4 weeks of form deprivation, the refractive power of the right eye in the FDM group was significantly higher than that in the left eye (
Our study highlights that the myopic mice have decreased R thickness, which might reflect the potential pathological mechanism of myopia.