AUTHOR=Arya Ravindra , Ervin Brian , Buroker Jason , Greiner Hansel M. , Byars Anna W. , Rozhkov Leonid , Skoch Jesse , Horn Paul S. , Frink Clayton , Scholle Craig , Leach James L. , Mangano Francesco T. , Glauser Tracy A. , Holland Katherine D. TITLE=Neuronal Circuits Supporting Development of Visual Naming Revealed by Intracranial Coherence Modulations JOURNAL=Frontiers in Neuroscience VOLUME=16 YEAR=2022 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2022.867021 DOI=10.3389/fnins.2022.867021 ISSN=1662-453X ABSTRACT=Background

Improvement in visual naming abilities throughout the childhood and adolescence supports development of higher-order linguistic skills. We investigated neuronal circuits underlying improvement in the speed of visual naming with age, and age-related dynamics of these circuits.

Methods

Response times were electronically measured during an overt visual naming task in epilepsy patients undergoing stereo-EEG monitoring. Coherence modulations among pairs of neuroanatomic parcels were computed and analyzed for relationship with response time and age.

Results

During the overt visual naming task, mean response time (latency) significantly decreased from 4 to 23 years of age. Coherence modulations during visual naming showed that increased connectivity between certain brain regions, particularly that between left fusiform gyrus/left parahippocampal gyrus and left frontal operculum, is associated with improvement in naming speed. Also, decreased connectivity in other brain regions, particularly between left angular and supramarginal gyri, is associated with decreased mean response time. Further, coherence modulations between left frontal operculum and both left fusiform and left posterior cingulate gyri significantly increase, while that between left angular and supramarginal gyri significantly decrease, with age.

Conclusion

Naming speed continues to improve from pre-school years into young adulthood. This age-related improvement in efficiency of naming environmental objects occurs likely because of strengthened direct connectivity between semantic and phonological nodes, and elimination of intermediate higher-order cognitive steps.