Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor
- 1School of Life Sciences, Xiamen University, Xiamen, China
- 2Neuropharmacology Laboratory of Physiology Department, Medical School of Nanchang University, Nanchang, China
- 3Department of Cell Biology, Medical School of Nanchang University, Nanchang, China
- 4Jiangxi Provincial Key Laboratory of Autonomic Nervous Function and Disease, Nanchang, China
A Corrigendum on
Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor
by Peng, L., Wu, B., Shi, L., Zou, L., Li, L., Yang, R., Xu, X., Li, G., Liu, S., Zhang, C., and Liang, S. (2021). Front. Neurosci. 15:663962. doi: 10.3389/fnins.2021.663962
In the original article, there was a mistake in Figure 4 as published. Incorrect images were used in Figures 4D,E. The corrected Figures 4D,E appear below.
Figure 4. Effects of uc.48+ on P2Y12 receptor expression and activation of P2Y12 downstream P38 MAPK pathway in vivo. Real-time PCR (A) and Western blotting (B) analyses showed siRNA silencing of uc.48+ downregulated P2Y12 receptor expression. n = 10 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. sham group, ##p < 0.01 vs. gp120 group. Real-time PCR (C) and Western blotting (D) results showed that overexpression of uc.48+ upregulated P2Y12 receptor levels in control rat DRG. n = 8 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. control group. (E–G) Uc.48+ siRNA lowered upregulated p-P38 MAPK levels in gp120 group. n = 10 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. sham group, ##p < 0.01 vs. gp120 group.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: dorsal root ganglia, HIV gp120-associated neuroinflammatory pain, long non-coding RNA, small interfering RNA, P2Y12 receptor
Citation: Peng L, Wu B, Shi L, Zou L, Li L, Yang R, Xu X, Li G, Liu S, Zhang C and Liang S (2021) Corrigendum: Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor. Front. Neurosci. 15:746945. doi: 10.3389/fnins.2021.746945
Received: 25 July 2021; Accepted: 01 November 2021;
Published: 26 November 2021.
Edited and reviewed by: Dominique Massotte, Université de Strasbourg, France
Copyright © 2021 Peng, Wu, Shi, Zou, Li, Yang, Xu, Li, Liu, Zhang and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Shangdong Liang, liangsd@hotmail.com
†These authors have contributed equally to this work