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CORRECTION article

Front. Neurosci., 26 November 2021
Sec. Neuropharmacology
This article is part of the Research Topic Purinergic Signaling and Neuroinflammation View all 6 articles

Corrigendum: Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor

\nLichao Peng&#x;Lichao Peng1Bing Wu,&#x;Bing Wu2,3Liran Shi,Liran Shi2,3Lifang Zou,Lifang Zou2,3Lin Li,Lin Li2,3Runan Yang,Runan Yang2,3Xiumei Xu,Xiumei Xu2,3Guilin Li,Guilin Li2,3Shuangmei Liu,Shuangmei Liu2,3Chunping Zhang,Chunping Zhang3,4Shangdong Liang,
Shangdong Liang2,3*
  • 1School of Life Sciences, Xiamen University, Xiamen, China
  • 2Neuropharmacology Laboratory of Physiology Department, Medical School of Nanchang University, Nanchang, China
  • 3Department of Cell Biology, Medical School of Nanchang University, Nanchang, China
  • 4Jiangxi Provincial Key Laboratory of Autonomic Nervous Function and Disease, Nanchang, China

A Corrigendum on
Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor

by Peng, L., Wu, B., Shi, L., Zou, L., Li, L., Yang, R., Xu, X., Li, G., Liu, S., Zhang, C., and Liang, S. (2021). Front. Neurosci. 15:663962. doi: 10.3389/fnins.2021.663962

In the original article, there was a mistake in Figure 4 as published. Incorrect images were used in Figures 4D,E. The corrected Figures 4D,E appear below.

FIGURE 4
www.frontiersin.org

Figure 4. Effects of uc.48+ on P2Y12 receptor expression and activation of P2Y12 downstream P38 MAPK pathway in vivo. Real-time PCR (A) and Western blotting (B) analyses showed siRNA silencing of uc.48+ downregulated P2Y12 receptor expression. n = 10 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. sham group, ##p < 0.01 vs. gp120 group. Real-time PCR (C) and Western blotting (D) results showed that overexpression of uc.48+ upregulated P2Y12 receptor levels in control rat DRG. n = 8 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. control group. (E–G) Uc.48+ siRNA lowered upregulated p-P38 MAPK levels in gp120 group. n = 10 rats per group. Data are displayed as means ± SEM. **p < 0.01 vs. sham group, ##p < 0.01 vs. gp120 group.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: dorsal root ganglia, HIV gp120-associated neuroinflammatory pain, long non-coding RNA, small interfering RNA, P2Y12 receptor

Citation: Peng L, Wu B, Shi L, Zou L, Li L, Yang R, Xu X, Li G, Liu S, Zhang C and Liang S (2021) Corrigendum: Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor. Front. Neurosci. 15:746945. doi: 10.3389/fnins.2021.746945

Received: 25 July 2021; Accepted: 01 November 2021;
Published: 26 November 2021.

Edited and reviewed by: Dominique Massotte, Université de Strasbourg, France

Copyright © 2021 Peng, Wu, Shi, Zou, Li, Yang, Xu, Li, Liu, Zhang and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Shangdong Liang, liangsd@hotmail.com

These authors have contributed equally to this work

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.