AUTHOR=Zhang Min , Wang Runhua , Luo Xin , Zhang Si , Zhong Xiaomei , Ning Yuping , Zhang Bin 

TITLE=Repetitive Transcranial Magnetic Stimulation Target Location Methods for Depression

JOURNAL=Frontiers in Neuroscience

VOLUME=15

YEAR=2021

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2021.695423

DOI=10.3389/fnins.2021.695423

ISSN=1662-453X

ABSTRACT=<p>Major depressive disorder (MDD) is a substantial global public health problem in need of novel and effective treatment strategies. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and promising treatment for depression that has been approved by the U.S. Food and Drug Administration (FDA). However, the methodological weaknesses of existing work impairs the universal clinical use of rTMS. The variation of stimulated targets across the dorsolateral prefrontal cortex may account for most of the heterogeneity in the efficacy of rTMS. Many rTMS target location methods for MDD have been developed in recent decades. This review was conducted to assess this emerging field and to improve treatment outcomes in clinical practice.</p>