AUTHOR=Wu Ying-Chang , Liao Ying-Siou , Yeh Wen-Hsiu , Liang Sheng-Fu , Shaw Fu-Zen 

TITLE=Directions of Deep Brain Stimulation for Epilepsy and Parkinson’s Disease

JOURNAL=Frontiers in Neuroscience

VOLUME=15

YEAR=2021

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2021.680938

DOI=10.3389/fnins.2021.680938

ISSN=1662-453X

ABSTRACT=<sec><title>Background</title><p>Deep brain stimulation (DBS) is an effective treatment for movement disorders and neurological/psychiatric disorders. DBS has been approved for the control of Parkinson disease (PD) and epilepsy.</p></sec><sec><title>Objectives</title><p>A systematic review and possible future direction of DBS system studies is performed in the open loop and closed-loop configuration on PD and epilepsy.</p></sec><sec><title>Methods</title><p>We searched Google Scholar database for DBS system and development. DBS search results were categorized into clinical device and research system from the open-loop and closed-loop perspectives.</p></sec><sec><title>Results</title><p>We performed literature review for DBS on PD and epilepsy in terms of system development by the open loop and closed-loop configuration. This study described development and trends for DBS in terms of electrode, recording, stimulation, and signal processing. The closed-loop DBS system raised a more attention in recent researches.</p></sec><sec><title>Conclusion</title><p>We overviewed development and progress of DBS. Our results suggest that the closed-loop DBS is important for PD and epilepsy.</p></sec>