AUTHOR=Panman Jessica L. , To Yang Yang , van der Ende Emma L. , Poos Jackie M. , Jiskoot Lize C. , Meeter Lieke H. H. , Dopper Elise G. P. , Bouts Mark J. R. J. , van Osch Matthias J. P. , Rombouts Serge A. R. B. , van Swieten John C. , van der Grond Jeroen , Papma Janne M. , Hafkemeijer Anne TITLE=Bias Introduced by Multiple Head Coils in MRI Research: An 8 Channel and 32 Channel Coil Comparison JOURNAL=Frontiers in Neuroscience VOLUME=13 YEAR=2019 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2019.00729 DOI=10.3389/fnins.2019.00729 ISSN=1662-453X ABSTRACT=
Neuroimaging MRI data in scientific research is increasingly pooled, but the reliability of such studies may be hampered by the use of different hardware elements. This might introduce bias, for example when cross-sectional studies pool data acquired with different head coils, or when longitudinal clinical studies change head coils halfway. In the present study, we aimed to estimate this possible bias introduced by using different head coils to create awareness and to avoid misinterpretation of results. We acquired, with both an 8 channel and 32 channel head coil, T1-weighted, diffusion tensor imaging and resting state fMRI images at 3T MRI (Philips Achieva) with stable acquisition parameters in a large group of cognitively healthy participants (