AUTHOR=Su Xiaojuan , Huang Lingyi , Xiao Dongqiong , Qu Yi , Mu Dezhi TITLE=Research Progress on the Role and Mechanism of Action of Activin A in Brain Injury JOURNAL=Frontiers in Neuroscience VOLUME=12 YEAR=2018 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2018.00697 DOI=10.3389/fnins.2018.00697 ISSN=1662-453X ABSTRACT=

Activin A belongs to the transforming growth factor superfamily and has a variety of biological functions. Studies have revealed that activin A can regulate the body's immune and inflammatory responses and participate in the regulation of cell death. In addition, activin A also has neurotrophic function and plays an important role in the repair of brain damage. This article summarizes recent advances in understanding the role and mechanism of action of activin A in brain injury and provides new hints into the application of activin A in the treatment of brain injury.