AUTHOR=Wang Junming , Sun Chenyou 

TITLE=Calcium and Neurogenesis in Alzheimer's Disease

JOURNAL=Frontiers in Neuroscience

VOLUME=4

YEAR=2010

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2010.00194

DOI=10.3389/fnins.2010.00194

ISSN=1662-453X

ABSTRACT=<p>It was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of Alzheimer's disease (AD). It remains, however, unclear how the calcium signaling are associated with in AD progression. Here we review recent studies to discuss the relationship among the signaling of intracellular calcium concentration, neurogenic activity, and AD progression. Analyzing these findings may provide new ideas to improve the neurogenic status in pathological processes in the aging brain.</p>