AUTHOR=Haraldsen Ira H. , Hatlestad-Hall Christoffer , Marra Camillo , Renvall Hanna , Maestú Fernando , Acosta-Hernández Jorge , Alfonsin Soraya , Andersson Vebjørn , Anand Abhilash , Ayllón Victor , Babic Aleksandar , Belhadi Asma , Birck Cindy , Bruña Ricardo , Caraglia Naike , Carrarini Claudia , Christensen Erik , Cicchetti Americo , Daugbjerg Signe , Di Bidino Rossella , Diaz-Ponce Ana , Drews Ainar , Giuffrè Guido Maria , Georges Jean , Gil-Gregorio Pedro , Gove Dianne , Govers Tim M. , Hallock Harry , Hietanen Marja , Holmen Lone , Hotta Jaakko , Kaski Samuel , Khadka Rabindra , Kinnunen Antti S. , Koivisto Anne M. , Kulashekhar Shrikanth , Larsen Denis , Liljeström Mia , Lind Pedro G. , Marcos Dolado Alberto , Marshall Serena , Merz Susanne , Miraglia Francesca , Montonen Juha , Mäntynen Ville , Øksengård Anne Rita , Olazarán Javier , Paajanen Teemu , Peña José M. , Peña Luis , Peniche Daniel lrabien , Perez Ana S. , Radwan Mohamed , Ramírez-Toraño Federico , Rodríguez-Pedrero Andrea , Saarinen Timo , Salas-Carrillo Mario , Salmelin Riitta , Sousa Sonia , Suyuthi Abdillah , Toft Mathias , Toharia Pablo , Tveitstøl Thomas , Tveter Mats , Upreti Ramesh , Vermeulen Robin J. , Vecchio Fabrizio , Yazidi Anis , Rossini Paolo Maria TITLE=Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment: the AI-Mind clinical study protocol JOURNAL=Frontiers in Neurorobotics VOLUME=17 YEAR=2024 URL=https://www.frontiersin.org/journals/neurorobotics/articles/10.3389/fnbot.2023.1289406 DOI=10.3389/fnbot.2023.1289406 ISSN=1662-5218 ABSTRACT=
More than 10 million Europeans show signs of mild cognitive impairment (MCI), a transitional stage between normal brain aging and dementia stage memory disorder. The path MCI takes can be divergent; while some maintain stability or even revert to cognitive norms, alarmingly, up to half of the cases progress to dementia within 5 years. Current diagnostic practice lacks the necessary screening tools to identify those at risk of progression. The European patient experience often involves a long journey from the initial signs of MCI to the eventual diagnosis of dementia. The trajectory is far from ideal. Here, we introduce the AI-Mind project, a pioneering initiative with an innovative approach to early risk assessment through the implementation of advanced artificial intelligence (AI) on multimodal data. The cutting-edge AI-based tools developed in the project aim not only to accelerate the diagnostic process but also to deliver highly accurate predictions regarding an individual's risk of developing dementia when prevention and intervention may still be possible. AI-Mind is a European Research and Innovation Action (RIA H2020-SC1-BHC-06-2020, No. 964220) financed between 2021 and 2026. First, the AI-Mind