REVIEW article

Front. Neurol.

Sec. Sleep Disorders

Volume 16 - 2025 | doi: 10.3389/fneur.2025.1586667

Research Trends and Hotspots of Central Sleep Apnea: A Bibliometric Analysis

Provisionally accepted
Yin-Chao  HaoYin-Chao HaoMengchu  ZhuMengchu ZhuWeixuan  LiWeixuan LiJing-Jing  ShaJing-Jing ShaXue-Tong  DongXue-Tong DongWang  SongjunWang SongjunChao-Long  LuChao-Long Lu*
  • Hebei Medical University, Shijiazhuang, China

The final, formatted version of the article will be published soon.

Central sleep apnea (CSA), characterized by unstable ventilatory control during sleep, poses significant health risks, particularly in patients with cardiovascular comorbidities. This bibliometric analysis evaluated 1,687 CSA-related publications (2004CSA-related publications ( -2025) ) from the Web of Science Core Collection. Annual publications surged post-2016, peaking in 2021 (115 articles), reflecting growing research interest. The U.S. and Germany dominated contributions, with American Journal of Respiratory and Critical Care Medicine as the top journal. Keyword analysis revealed three focal areas: CSA-heart failure interactions (e.g., mortality, ejection fraction), CSA mechanisms (e.g., hypercapnia, chemosensitivity), and clinical management (e.g., adaptive servo-ventilation, phrenic nerve stimulation). Emerging trends include pediatric CSA, pathophysiology, and AI-driven diagnostics. International collaboration and multidisciplinary approaches are critical for advancing CSA research. Limitations include database constraints and evolving literature. This study maps CSA research trends, highlights gaps, and guides future investigations into mechanisms, biomarkers, and personalized therapies.

Keywords: central sleep apnea, bibliometrics analysis, Citespace, VOSviewer, CSA

Received: 03 Mar 2025; Accepted: 24 Apr 2025.

Copyright: © 2025 Hao, Zhu, Li, Sha, Dong, Songjun and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Chao-Long Lu, Hebei Medical University, Shijiazhuang, China

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