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REVIEW article
Front. Neurol.
Sec. Neurotechnology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1582325
Visualization Analysis of Literature on the Current State of Vagus Nerve Stimulation Research
Provisionally accepted
Xia Jiang*
Lina Zhang- Chongqing Three Gorges Central Hospital, Chongqing, China
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This study conducts a comprehensive bibliometric and visual analysis of 7,725 publications related to Vagus Nerve Stimulation (VNS) sourced from the Web of Science database up to June 26, 2024. Utilizing tools such as VOSviewer and CiteSpace, we examined publication trends, global research distribution, leading institutions, highly cited works, and emerging research hotspots in the VNS field. The analysis revealed a significant increase in VNS-related publications from 2010 to 2020, predominantly led by high-income countries like the United States, Germany, and the United Kingdom, with notable contributions from China and Japan. Key research institutions, including Harvard Medical School and the University of California, Los Angeles, play pivotal roles in advancing VNS applications across various domains such as epilepsy, depression, chronic pain, cardiovascular diseases, inflammatory conditions, and neurorehabilitation. Highly cited articles in prestigious journals like Nature underscore the foundational and impactful nature of VNS research. Keyword analysis identified major research clusters and evolving trends, highlighting VNS's expanding therapeutic potential and the integration of personalized treatment approaches. The findings provide a detailed overview of the development trajectory of VNS research, emphasizing its global collaborative efforts and diverse clinical applications, thereby offering valuable insights for future research directions and strategic collaborations in the field.
Keywords: Vagus Nerve Stimulation, visual analysis, Epilepsy, Depression, Stroke
Received: 24 Feb 2025; Accepted: 11 Apr 2025.
Copyright: © 2025 Jiang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xia Jiang, Chongqing Three Gorges Central Hospital, Chongqing, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.