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ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neuromuscular Disorders and Peripheral Neuropathies
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1574807
Comprehensive analysis of partial confounding clinical symptoms and treatment options of botulism: a case series
Provisionally accepted- 1 Second Xiangya Hospital, Central South University, Changsha, China
- 2 Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China
Objective: To examine the clinical presentations, and therapeutic principles of botulism, with the goal of improving physicians' understanding of the condition and refining treatment strategies.Method: A retrospective analysis was carried out on the clinical data of 8 patients with botulism, encompassing age, gender, etiology, delay diagnosis time, course of disease, clinical manifestations, auxiliary examinations, and treatment.Results: Among the 8 cases, 5 were female and 3 male, with the age ranging from 14 to 60 years. 5 cases were of iatrogenic poisoning, and 3 were of foodborne poisoning. Besides the classical clinical manifestations, some patients had atypical symptoms like intestinal obstruction, unilateral involvement, and consciousness disorder. Among the 8 cases, 6 had abnormal electrophysiological examination results. 6 patients had a delayed diagnosis of over 7 days, with disease course from 7 to 115 days, and 7 received treatment. All patients received symptomatic
Keywords: Botulism, Atypical symptoms, Neurophysiological studies, Delay diagnosis, Treatment
Received: 11 Feb 2025; Accepted: 24 Mar 2025.
Copyright: © 2025 Huang, Hu, Xiao and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zhiping Hu, Second Xiangya Hospital, Central South University, Changsha, China
Han Xiao, Second Xiangya Hospital, Central South University, Changsha, China
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