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CASE REPORT article
Front. Neurol.
Sec. Multiple Sclerosis and Neuroimmunology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1559872
This article is part of the Research Topic Exploring the Interplay Between Microbiota, Gut, and Brain in Inflammatory Bowel Disease View all articles
Very-Late-Onset Neuromyelitis Optica Spectrum Disorder: A Case Report and Review
Provisionally accepted- 1 University of Jinan, Jinan, China
- 2 Jinan Central Hospital, Jinan, Shandong Province, China
- 3 Shandong University, Jinan, Shandong Province, China
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that causes demyelination within the central nervous system, typically manifesting as symptoms of optic neuritis and myelitis. We report the case of a 92-year-old patient with NMOSD who was admitted to our hospital; hers is currently the oldest reported case of NMOSD globally. The onset occurred after COVID-19 vaccination, and the patient responded well to treatment with satralizumab.
Keywords: We thank Claire Barnes, PhD, from Liwen Bianji (Edanz) NMOSD, very-late-onset, COVID-19 vaccine, Satralizumab
Received: 13 Jan 2025; Accepted: 24 Feb 2025.
Copyright: © 2025 Liu, Guo, Du and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Heng Li, Jinan Central Hospital, Jinan, 250000, Shandong Province, China
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