AUTHOR=Zheng Hao-tao , Lai Wen-wen , Wang Jian-jun , Kong Fan-xin , Cai Hao-bin , Lin Song-jun , Wang Xu , Cai Dong-bin , Pi Min , Qin Xiu-de TITLE=Association between methylenetetrahydrofolate reductase C677T polymorphism and cerebral small vessel disease: a systematic review and meta-analysis JOURNAL=Frontiers in Neurology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1556535 DOI=10.3389/fneur.2025.1556535 ISSN=1664-2295