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ORIGINAL RESEARCH article

Front. Neurol.

Sec. Neuromuscular Disorders and Peripheral Neuropathies

Volume 16 - 2025 | doi: 10.3389/fneur.2025.1546773

Ultrasound-Guided Injection of Platelet-Rich Plasma for Treatment of Traumatic Painful Neuroma of the Brachial Plexus: A Case Report and Literature Review

Provisionally accepted
Haifeng Zhu Haifeng Zhu 1,2*Zixuan Deng Zixuan Deng 1,2Yongqi Xie Yongqi Xie 1,2Guifeng Qian Guifeng Qian 1,2Danyu Wang Danyu Wang 2,3Shaodong Xie Shaodong Xie 1,2*Yunyi Zhang Yunyi Zhang 1,2Peichun Yan Peichun Yan 1,2
  • 1 Department of Rehabilitation Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong Province, China
  • 2 The Eighth Clinical Medical College, Foshan Hospital of Traditional Chinese Medicine, Foshan City, China
  • 3 Department of Ultrasound Diagnosis and Treatment, Foshan Hospital of Traditional Chinese Medicine, Fohan, China

The final, formatted version of the article will be published soon.

    Traumatic neuroma (TN) is a repair response of nerves to direct/indirect trauma or chronic inflammatory injury, commonly occurring after trauma or surgery. The authors report a rare case of a traumatic painful neuroma of the brachial plexus. Physical therapy and drug treatment failed to resolve the symptoms of allodynia and a palpable mass, which significantly reduced the patient's quality. Ultrasound-guided injection of platelet-rich plasma (PRP) has shown significant efficacy in repairing the nerve and relieving pain. However, there is a lack of research on treating TN with PRP injection. This case demonstrates that ultrasound-guided injection of PRP can alleviate neuropathic pain caused by a traumatic painful neuroma of brachial plexus and improve the upper limb function.

    Keywords: Neuroma, Brachial Plexus, Platelet-Rich Plasma, Ultrasonography, interventional, neuropathic pain 1

    Received: 17 Dec 2024; Accepted: 24 Feb 2025.

    Copyright: © 2025 Zhu, Deng, Xie, Qian, Wang, Xie, Zhang and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Haifeng Zhu, Department of Rehabilitation Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong Province, China
    Shaodong Xie, Department of Rehabilitation Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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