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ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neurocritical and Neurohospitalist Care
Volume 16 - 2025 |
doi: 10.3389/fneur.2025.1539213
Ultrasound-based measurement of optic nerve sheath to evaluate increased intracranial pressure on patients in emergency department
Provisionally accepted- 1 Department of Ultrasound Imaging, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
- 2 Institute of Hepatology and Epidemiology, Hangzhou Xixi Hospital, Hangzhou, China
- 3 Department of Ultrasound, Hangzhou Xixi Hospital, Hangzhou, China
Recent studies reported that non-invasive imaging techniques for measuring optic nerve sheath diameter (ONSD) offer a novel diagnostic approach for intracranial pressure (ICP) elevation. However, whether ultrasound-measured ONSD dynamically and sensitively evaluate the real-time ICP is unknown. This study explores the ability of different measurement modalities to predict ICP elevation, aiming to provide a superior non-invasive ICP monitoring technique for clinical practice.Optic nerve sheath (ONS) measurement using three modalities and ICP of 104 patients collected from January 2018 to May 2021 were analysis by correlation analysis and receiver operating characteristic curve analysis.Significant correlations were observed between ICP and ONS measurement using three modalities (P < 0.001). According to the ROC analysis, if ONS long diameter > 5.55 mm, ONS vertical diameter > 5.75 mm, left ONS area > 25.05 mm² or right ONS area > 25.73 mm² , the patient was considered to have elevated ICP.Ultrasonic transverse scanning, longitudinal scanning, and area-based measurement of the retrobulbar ONS are excellent screening tools for the diagnosis of ICP. These three methods exhibited nearly identical levels of correlation, sensitivity, and specificity. All three measurement approaches demonstrated capabilities in diagnosing elevated ICP.
Keywords: Intracranial Pressure, Optic nerve sheath, ultrasound, diagnostics, emergency department
Received: 09 Dec 2024; Accepted: 26 Jan 2025.
Copyright: © 2025 Jiang, Shao, Pan and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hai-Dan Jiang, Department of Ultrasound Imaging, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China
Lin Pan, Department of Ultrasound, Hangzhou Xixi Hospital, Hangzhou, China
Hui Li, Department of Ultrasound Imaging, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China
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