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REVIEW article
Front. Neurol.
Sec. Stroke
Volume 16 - 2025 |
doi: 10.3389/fneur.2025.1513574
This article is part of the Research Topic Small Vessel Disease: Cause of Cerebral Infarction without Large Vessel Occlusion View all 4 articles
Advances in the Study of Apathy Related to Cerebral Small Vessel Disease
Provisionally accepted- Hebei General Hospital, Shijiazhuang, China
Cerebral small vessel disease (CSVD) is a complex clinical-imaging pathological syndrome caused by small vessel lesions in the brain, which is characterized by agingrelated, insidious onset and slow progression. Apathy is a key component of the common neuropsychiatric symptoms among CSVD patients, severely affecting their daily lives and social functioning. Moreover, there are fewer studies on CSVD-related apathy, and greater attention should be paid to this condition in clinical practice. This article describes the latest research advances in the concept, epidemiological features, pathogenesis, assessment and diagnosis, imaging and biomarkers, and treatment of CSVD-related apathy, aiming to serve as a reference for the clinical diagnosis and prevention of CSVD-related apathy.
Keywords: Cerebral small vessel disease, Apathy, Pathogenesis, biomarker, Treatment
Received: 18 Oct 2024; Accepted: 31 Jan 2025.
Copyright: © 2025 BU, HU, SU and LI. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Li-tao LI, Hebei General Hospital, Shijiazhuang, China
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